Peter Gardner Lab
University of Manchester
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Paul Bassan
 
2003-2006: BSc Physics, University of Warwick, UK
 
2006-2007: MSc Medical Physics, University of Manchester, UK
 
2007-2011: PhD Analytical Science, University of Manchester, UK
  • Biomedical Fourier transform infared (FTIR) spectroscopy of highly scattering samples: Understanding and correcting resonant Mie scattering (RMieS).
 
 

  
Profile:
 

Paul Bassan received his B.Sc. in Physics at the University of Warwick U.K. in 2006 and then went on to receive an M.Sc. in Medical Physics at the University of Manchester U.K. in 2007. In October 2007 he joined the Gardner group at the University of Manchester and is currently researching the fundamental principles of mid-IR light scattering (namely Mie scattering) in single cell and tissue samples as used in FTIR spectroscopy. Eventual aims are to produce a correction algorithm which recovers the pure absorbance spectra of highly scattering samples. A preliminary version called the resonant Mie scattering extended multiplicative signal correction (RMieS-EMSC) has been written (in collaboration with Achim Kohler  and Harald Martens of Nofima Mat, Norway) and distributed free of charge to academic users. In the future he plans to apply the RMieS-EMSC to FTIR imaging data with the use of parallel computing using graphics processing unit (GPU) computing.
 
 
Areas of expertise:
 
 
Publications:
 
Paul Bassan, and Peter Gardner, Chapter 8: Scattering in Biomedical Infrared Spectroscopy, in Biomedical Applications of Synchrotron Infrared Microspectroscopy, The Royal Society of Chemistry. p. 260-276.
 
Paul Bassan, Achim Kohler, Harald Martens, Joe Lee, Edward Jackson, Nicholas Lockyer, Paul Dumas, Michael Brown, Noel Clarke and Peter Gardner. "RMieS-EMSC correction for infrared spectra of biological cells: Extension using full Mie theory and GPU computing".  Journal of Biophotonics (accepted)

Paul Bassan, Achim Kohler, Harald Martens, Joe Lee, Hugh J. Byrne, Paul Dumas, Ehsan Gazi, Michael Brown, Noel Clarke and Peter Gardner. "Resonant Mie Scattering (RMieS) correction of infrared spectra from highly scattering samples". Analyst, 135, 268-277 (2010)

Paul Bassan, Hugh J. Byrne, Franck Bonnier, Joe Lee, Paul Dumas and Peter Gardner. "Resonant Mie scattering in infrared spectroscopy of biological materials - understanding the 'dispersion artefact'. Analyst, 134, 1586-1593 (2009)

Paul Bassan, Hugh J. Byrne, Joe Lee, Franck Bonnier, Colin Clarke, Paul Dumas, Ehsan Gazi, Michael D. Brown, Noel W. Clarke and Peter Gardner. "Reflection contributions to the dispersion artefact in FTIR spectra of single biological cells". Analyst, 134, 1171-1175 (2009)